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N-Boc-N-bis (PEG4-OH)

N-Boc-N-bis (PEG4-OH) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. N-Boc-N-bis (PEG4-OH) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1].

Product Specifications

CAS Number

[2093154-01-7]

UNSPSC

12352203

Hazard Statement

H302-H315-H319-H335

Target

ADC Linker; PROTAC Linkers

Type

ADC Related

Related Pathways

Antibody-drug Conjugate/ADC Related; PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/n-boc-n-bis-peg4-oh.html

Solubility

10 mM in DMSO

Smiles

O=C(OC(C)(C)C)N(CCOCCOCCOCCO)CCOCCOCCOCCO

Molecular Formula

C21H43NO10

Molecular Weight

469.57

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

References & Citations

[1]Alain Wagner, et al. Intra-droplet surface engineering to capture a molecular target. WO2017174610A1.

Shipping Conditions

Room temperature

Scientific Category

ADC Related

Clinical Information

No Development Reported

Isoform

Alkyl/ether Linkers; Cleavable Linker; PEG Linkers

Available Sizes

Curated Selection

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