Leukotriene F4
Leukotriene F4 (LTF4), is a lipid that belongs to the Cysteinyl Leukotriene (CysTL) family[1]. Leukotriene F4 induces bronchoconstriction with an ED50 of 16 μg/kg[2]. The precursor of LTF4 is Leukotriene E4 (LTE4), which isformed from the action of a glutamyl transferase[1].
Product Specifications
CAS Number
[83851-42-7]
UNSPSC
12352211
Hazard Statement
H225-H301+H311+H331-H370
Target
Endogenous Metabolite; Leukotriene Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/leukotriene-f4.html
Solubility
10 mM in DMSO
Smiles
O=C(O)[C@H](CS[C@@H]([C@@H](O)CCCC(O)=O)/C=C/C=C/C=C\C/C=C\CCCCC)NC(CC[C@@H](C(O)=O)N)=O
Molecular Formula
C28H44N2O8S
Molecular Weight
568.72
Precautions
References & Citations
[1]Reddanna P, et al. Carboxypeptidase A-catalyzed direct conversion of leukotriene C4 to leukotriene F4. Arch Biochem Biophys. 2003;413 (2) :158-163.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Human Endogenous Metabolite
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