Propargyl-PEG8-OH

Propargyl-PEG8-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. Propargyl-PEG8-OH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Product Specifications

CAS Number

[1351556-81-4]

UNSPSC

12352211

Hazard Statement

H302-H315-H319-H335

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/propargyl-peg8-oh.html

Solubility

10 mM in DMSO

Smiles

C#CCOCCOCCOCCOCCOCCOCCOCCOCCO

Molecular Formula

C19H36O9

Molecular Weight

408.48

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

References & Citations

[1]Goswami LN, et al. Efficient synthesis of diverse heterobifunctionalized clickable oligo (ethylene glycol) linkers: potential applications in bioconjugation and targeted drug delivery. Org Biomol Chem. 2013 Feb 21;11 (7) :1116-26.