α-Guanidinoglutaric acid

α-Guanidinoglutaric acid is a guanidino compound first found in cobaltinduced epileptogenic focus tissue in the cerebral cortex of cats. α-Guanidinoglutaric acid induces epileptic seizures in rats after intraventricular administration[1].

Product Specifications

CAS Number

[73477-53-9]

UNSPSC

12352211

Hazard Statement

H302-H315-H319-H335

Target

NO Synthase

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/α-guanidinoglutaric-acid.html

Solubility

10 mM in DMSO

Smiles

O=C(O)CC[C@@H](C(O)=O)NC(N)=N

Molecular Formula

C6H11N3O4

Molecular Weight

189.17

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

References & Citations

[1]H Shiraga, et al. Convulsive activity of alpha-guanidinoglutaric acid and the possible involvement of 5-hydroxytryptamine in the alpha-guanidinoglutaric acid-induced seizure mechanism. J Neurochem. 1986 Dec;47 (6) :1832-6.