NF864

NF864 is a selectivelyP2X1 receptorinhibitor in human platelets[1].

Product Specifications

CAS Number

69606-09-3

UNSPSC

12352005

Target

P2X Receptor

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/nf864.html

Solubility

10 mM in DMSO

Smiles

O=C(NC1=CC(C(NC2=CC=C(S(=O)(O[Na])=O)C3=CC(S(=O)(O[Na])=O)=CC(S(=O)(O[Na])=O)=C23)=O)=CC(C(NC4=CC=C(S(=O)(O[Na])=O)C5=CC(S(=O)(O[Na])=O)=CC(S(=O)(O[Na])=O)=C45)=O)=C1)NC6=CC(C(NC7=CC=C(S(=O)(O[Na])=O)C8=CC(S(=O)(O[Na])=O)=CC(S(=O)(O[Na])=O)=C78)=O)=CC(C(NC9=CC=C(S(=O)(O[Na])=O)C%10=CC(S(=O)(O[Na])=O)=CC(S(=O)(O[Na])=O)=C9%10)=O)=C6

Molecular Formula

C57H28N6Na12O41S12

Molecular Weight

2113.51

References & Citations

[1]Horner S, et al. The novel suramin analogue NF864 selectively blocks P2X1 receptors in human platelets with potency in the low nanomolar range. Naunyn Schmiedebergs Arch Pharmacol. 2005;372 (1) :1-13.