PDE1-IN-3

PDE1-IN-3, compound 4 (WO2019156861), is a selective human phosphodiesterase 1 (PDE1) inhibitor. PDE1-IN-3 inhibits PDE4D and PDE6AB with IC50 values of 23.99 μM and 10 μM, respectively[1].

Product Specifications

CAS Number

[2370966-46-2]

UNSPSC

12352005

Target

Phosphodiesterase (PDE)

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/pde1-in-3.html

Solubility

10 mM in DMSO

Smiles

O=C1C2=NN=C(C3(C4CC4)CC3)N2C(C)=C(C)N1CC5CCC5

Molecular Formula

C18H24N4O

Molecular Weight

312.41

References & Citations

[1]Nicholas Paul Camp, et al. [1,2,4]triazolo[4,3-a]pyrazin-8-one derivatives

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

PDE1

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

MP204441 200 Reactions

Ercc3 Mouse qPCR Primer Pair (NM_133658)

Ask

View Details

NBP2-71069B 0.1 mL

Mouse Monoclonal Ketohexokinase Antibody (OTI1D8) [Biotin]

Ask

View Details

MBS4753339-01 0.1 mL

MBNL1 Rabbit mAb

Ask

View Details

MBS4753339-02 5x 0.1 mL

MBNL1 Rabbit mAb

Ask

View Details

MBS1198005-01 0.02 mg (E-Coli)

Recombinant Escherichia coli Putative uncharacterized protein ytfA (ytfA)

Ask

View Details

MBS1198005-02 0.1 mg (E-Coli)

Recombinant Escherichia coli Putative uncharacterized protein ytfA (ytfA)

Ask

View Details