PDE1-IN-3
PDE1-IN-3, compound 4 (WO2019156861), is a selective human phosphodiesterase 1 (PDE1) inhibitor. PDE1-IN-3 inhibits PDE4D and PDE6AB with IC50 values of 23.99 μM and 10 μM, respectively[1].
Product Specifications
CAS Number
[2370966-46-2]
UNSPSC
12352005
Target
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/pde1-in-3.html
Solubility
10 mM in DMSO
Smiles
O=C1C2=NN=C(C3(C4CC4)CC3)N2C(C)=C(C)N1CC5CCC5
Molecular Formula
C18H24N4O
Molecular Weight
312.41
References & Citations
[1]Nicholas Paul Camp, et al. [1,2,4]triazolo[4,3-a]pyrazin-8-one derivatives
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PDE1
Curated Selection
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