Psoromic acid
Psoromic acid is a potent and selective RabGGTase (Rab geranylgeranyl transferase) inhibitor with an IC50 value of 1.3 µM. Psoromic acid is an antioxidative agent. Psoromic acid exhibits a competitive type of HMGR inhibition and mixed type of ACE (angiotensin converting enzyme) inhibition[1][2].
Product Specifications
CAS Number
7299-11-8
Product Name Alternative
Parellic acid
UNSPSC
12352005
Target
Others
Type
Natural Products
Related Pathways
Others
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/psoromic-acid.html
Purity
99.2
Solubility
DMSO : 7.17 mg/mL (ultrasonic; warming)
Smiles
OC(C(C=C1OC)=C(OC(C2=C3C)=C(C(O)=C3)C=O)C(OC2=O)=C1C)=O
Molecular Formula
C18H14O8
Molecular Weight
358.30
References & Citations
[1]Deraeve C, et al. Psoromic acid is a selective and covalent Rab-prenylation inhibitor targeting autoinhibited RabGGTase. J Am Chem Soc. 2012 May 2;134 (17) :7384-91.|[2]Behera BC, et al. Antioxidative and cardiovascular-protective activities of metabolite usnic acid and psoromic acid produced by lichen species Usnea complanata under submerged fermentation. Pharm Biol. 2012 Aug;50 (8) :968-79.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
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