Propargyl-PEG5-OH
Propargyl-PEG5-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG5-OH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Product Specifications
CAS Number
[1036204-60-0]
UNSPSC
12352211
Hazard Statement
H315, H319, H335
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/propargyl-peg5-oh.html
Purity
99.48
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OCCOCCOCCOCCOCCOCC#C
Molecular Formula
C13H24O6
Molecular Weight
276.33
Precautions
H315, H319, H335
References & Citations
[1]Robert Zamboni, et al. Raf-degrading conjugate compounds. WO2018200981A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PEG Linkers
Available Sizes
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