Sucunamostat (hydrate)
Sucunamostat hydrate (SCO-792) is an orally active and reversible enteropeptidase inhibitor with IC50s of 4.6 nM and 5.4 nM for rat enteropeptidase and human enteropeptidase, respectively. Sucunamostat hydrate can slowly dissociate from enteropeptidase in vitro and inhibit protein digestion in vivo[1].
Product Specifications
Product Name Alternative
SCO-792
UNSPSC
12352005
Target
Enteropeptidase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/sucunamostat-hydrate.html
Solubility
10 mM in DMSO
Smiles
O=C(O)C[C@@H](C(O)=O)NC(C[C@@H]1COC2=CC(OC(C3=CC=C(NC(N)=N)C=C3)=O)=CC=C12)=O.[x].O
Molecular Formula
C22H22N4O8.xH2O
References & Citations
[1]Sasaki M, et al. Discovery and characterization of a small-molecule enteropeptidase inhibitor, SCO-792. Pharmacol Res Perspect. 2019 Sep 4;7 (5) :e00517.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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