IACS-8803
IACS-8803 is a highly potent cyclic dinucleotide STING agonist with robust systemic antitumor efficacy[1].
Product Specifications
CAS Number
2095690-70-1
UNSPSC
12352005
Target
STING
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/iacs-8803.html
Purity
99.24
Solubility
H2O : 15 mg/mL (ultrasonic)
Smiles
NC1=NC=NC2=C1N=CN2[C@H]3[C@H](F)[C@H](O[P@@]4(S)=O)[C@@H](CO[P@](O[C@@H]5[C@H](O)[C@@H](CO4)O[C@H]5N(C=N6)C7=C6C(N)=NC=N7)(S)=O)O3
Molecular Formula
C20H23FN10O9P2S2
Molecular Weight
692.53
References & Citations
[1]Ager CR, et al. Discovery of IACS-8803 and IACS-8779, potent agonists of stimulator of interferon genes (STING) with robust systemic antitumor efficacy. Bioorg Med Chem Lett. 2019 Oct 15;29 (20) :126640.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
D9984 96 Tests
Hepatocyte Growth Factor Like protein (MST1) Bovine ELISA Kit
Sign In for Pricing
View Details 
NBL1-10990 0.1 mg
Glucosylceramidase/GBA Overexpression Lysate (Native) - (Dry Ice)
Sign In for Pricing
View Details MP0665J Each
Magic™ Membrane Protein Human MEST (Mesoderm specific transcript) for Antibody Discovery
Sign In for Pricing
View Details