16-Epiestriol

16-Epiestriol is a metabolite of the endogenous estrogen estrone with antibacterial and anti-inflammatory effects[1][2][3].

Product Specifications

CAS Number

[547-81-9]

Product Name Alternative

16-epi-Estriol; 16β,17β-Estriol

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Bacterial; Endogenous Metabolite

Type

Reference compound

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/16-epiestriol.html

Purity

99.04

Solubility

10 mM in DMSO

Smiles

C[C@@]12[C@@H](O)[C@@H](O)C[C@@]1([H])[C@]3([H])CCC4=C(C=CC(O)=C4)[C@@]3([H])CC2

Molecular Formula

C18H24O3

Molecular Weight

288.38

Precautions

H302, H315, H319, H335

References & Citations

[1]Brinton LA, et al. Serum Estrogens and Estrogen Metabolites and Endometrial Cancer Risk among Postmenopausal Women. Cancer Epidemiol Biomarkers Prev. 2016 Jul;25 (7) :1081-9. ; Skariyachan S, et al. Natural epiestriol-16 act as potential lead molecule against prospective molecular targets of multidrug resistant Acinetobacter baumannii-Insight from in silico modelling and in vitro investigations. Infect Genet Evol. 2020 Aug;82:104314.; Latman NS, et al. 16-epiestriol: an anti-inflammatory steroid without glycogenic activity. J Pharm Sci. 1994 Jun;83 (6) :874-7.