Anticancer agent 173

Anticancer agent 173 (compound 19) is a potent thioxodihydroquinazolinone analogs when combined with platinum drugs in inducing apoptotic cancer cells death[1].

Product Specifications

CAS Number

[177951-34-7]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Apoptosis

Type

Reference compound

Related Pathways

Apoptosis

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Infection

Assay Protocol

https://www.medchemexpress.com/anticancer-agent-173.html

Solubility

10 mM in DMSO

Smiles

O=C1N(C2=CC=CC=C2CC)C(NC3=C1C=CC=C3)=S

Molecular Formula

C16H14N2OS

Molecular Weight

282.36

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

References & Citations

[1]Jing Ma, et al. Combination of a thioxodihydroquinazolinone with cisplatineliminates ovarian cancer stem cell-like cells (CSC-LCs) andshows preclinical potential. Oncotarget. 2017 Dec 26;9 (5) :6042-6054.