D-NAME (hydrochloride)

D-NAME (D-NG-nitroarginine methyl ester) hydrochloride is a potent nitric oxide synthase (NOS) inhibitor. D-NAME hydrochloride inhibits the activity of NOS, reducing the production of nitric oxide[1].

Product Specifications

CAS Number

[50912-92-0]

Product Name Alternative

D-NG-nitroarginine methyl ester (hydrochloride) ; H-D-Arg (NO2) -OMe (hydrochloride)

UNSPSC

12352211

Hazard Statement

H228-H302+H312+H332-H315-H319

Target

NO Synthase

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/d-name-hydrochloride.html

Solubility

10 mM in DMSO

Smiles

N[C@H](CCCNC(N[N+]([O-])=O)=N)C(OC)=O.[H]Cl

Molecular Formula

C7H16ClN5O4

Molecular Weight

269.69

Precautions

P210-P240-P241-P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P370+P378-P501

References & Citations

[1]Palmer RM, et, al. L-arginine is the physiological precursor for the formation of nitric oxide in endothelium-dependent relaxation. Biochem Biophys Res Commun. 1988 Jun 30;153 (3) :1251-6.