Z-Leu-Leu-Leu-AMC
Z-Leu-Leu-Leu-AMC is a fluorogenic substrate for measuring the chymotrypsin-like protease activity of the 20S proteasome[1].
Product Specifications
CAS Number
[152015-61-7]
Product Name Alternative
Z-LLL-AMC
UNSPSC
12352209
Target
Proteasome
Type
Peptides
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/z-leu-leu-leu-amc.html
Purity
98.4
Solubility
10 mM in DMSO
Smiles
CC(C1=CC=C(NC([C@H](CC(C)C)NC([C@H](CC(C)C)NC([C@H](CC(C)C)NC(OCC2=CC=CC=C2)=O)=O)=O)=O)C=C1O3)=CC3=O
Molecular Formula
C36H48N4O7
Molecular Weight
648.79
References & Citations
[1]McNaught KS, et al. Proteasomal function is impaired in substantia nigra in Parkinson's disease. Neurosci Lett. 2001 Jan 19;297 (3) :191-4.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
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