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Z-Leu-Leu-Leu-AMC

Z-Leu-Leu-Leu-AMC is a fluorogenic substrate for measuring the chymotrypsin-like protease activity of the 20S proteasome[1].

Product Specifications

CAS Number

152015-61-7

Product Name Alternative

Z-LLL-AMC

UNSPSC

12352209

Target

Proteasome

Type

Peptides

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/z-leu-leu-leu-amc.html

Purity

98.4

Solubility

10 mM in DMSO

Smiles

CC(C1=CC=C(NC([C@H](CC(C)C)NC([C@H](CC(C)C)NC([C@H](CC(C)C)NC(OCC2=CC=CC=C2)=O)=O)=O)=O)C=C1O3)=CC3=O

Molecular Formula

C36H48N4O7

Molecular Weight

648.79

References & Citations

[1]McNaught KS, et al. Proteasomal function is impaired in substantia nigra in Parkinson's disease. Neurosci Lett. 2001 Jan 19;297 (3) :191-4.

Shipping Conditions

Blue Ice

Storage Conditions

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

Scientific Category

Peptides

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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