GLP-1 receptor agonist 3
GLP-1 receptor agonist 3 (compound (R) -4A-1) is a GLP-1 receptor agonist (WO2018109607A1), used for diabetes research. compound (S) -4A-1 shows EC50s of 1.1 nM and 13 nM in Clone H6 and Clone C6 cell lines assay, respectively[1].
Product Specifications
CAS Number
2230200-09-4
UNSPSC
12352005
Target
GCGR
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/glp-1-receptor-agonist-3.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC=C2N=C(CN3CCC(C4=NC(OCC5=CC=C(C#N)C=C5F)=CC=C4)CC3)N(C[C@@H]6OCC6)C2=C1)O
Molecular Formula
C31H30FN5O4
Molecular Weight
555.60
References & Citations
[1]Gary Erik Aspnes, et al. Glp-1 receptor agonists and uses thereof. WO2018109607A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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