NH2-PEG5-OH
NH2-PEG5-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. NH2-PEG5-OH is also a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [2].
Product Specifications
CAS Number
[34188-11-9]
UNSPSC
12352203
Hazard Statement
H302, H315, H319, H335
Target
ADC Linker; PROTAC Linkers
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/nh2-peg5-oh.html
Purity
99.82
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OCCOCCOCCOCCOCCN
Molecular Formula
C10H23NO5
Molecular Weight
237.29
Precautions
H302, H315, H319, H335
References & Citations
[1]Nathanael Gray, et al. Bifunctional molecules for degradation of egfr and methods of use. WO2017185036A1.|[2]Nianhe Han, et al. Derivatives of dolastatin 10 and uses thereof. WO2016192527A1.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Non-cleavable Linker; PEG Linkers
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS6311503-01 0.2 mL
JAK2, CT (JAK2, Tyrosine-protein kinase JAK2, Janus kinase 2) (Azide free) (HRP)
Ask
View Details 
MBS6311503-02 5x 0.2 mL
JAK2, CT (JAK2, Tyrosine-protein kinase JAK2, Janus kinase 2) (Azide free) (HRP)
Ask
View Details