NH2-PEG5-OH
Product Specifications
UNSPSC Description
NH2-PEG5-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. NH2-PEG5-OH is also a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2].
Target Antigen
ADC Linker; PROTAC Linkers
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related;PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/nh2-peg5-oh.html
Purity
98.0
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OCCOCCOCCOCCOCCN
Molecular Weight
237.29
References & Citations
[1]Nathanael Gray, et al. Bifunctional molecules for degradation of egfr and methods of use. WO2017185036A1.|[2]Nianhe Han, et al. Derivatives of dolastatin 10 and uses thereof. WO2016192527A1.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-129637/NH2-PEG5-OH-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-129637/NH2-PEG5-OH-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
34188-11-9
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