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NO2-SPP

NO2-SPP is a cleavable linker that is used for making antibody-drug conjugate (ADC) .

Product Specifications

CAS Number

[663598-61-6]

UNSPSC

12352203

Hazard Statement

H302-H315-H319-H335

Target

ADC Linker

Type

ADC Related

Related Pathways

Antibody-drug Conjugate/ADC Related

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/no2-spp.html

Solubility

10 mM in DMSO

Smiles

CC(SSC1=NC=C([N+]([O-])=O)C=C1)CCC(ON2C(CCC2=O)=O)=O

Molecular Formula

C14H15N3O6S2

Molecular Weight

385.42

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

References & Citations

[1]Qiming Chen, et al. Anti-integrin immunoconjugates, methods and uses. WO2006062779A2.

Shipping Conditions

Room temperature

Scientific Category

ADC Related

Clinical Information

No Development Reported

Isoform

Cleavable Linker; Disulfide Cleavable Linker

Curated Selection

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