Ala-Ala-Asn-PAB (TFA)
Ala-Ala-Asn-PAB TFA is a peptide cleavable ADC linker for antibody-drug conjugates (ADCs) [1].
Product Specifications
UNSPSC
12352005
Target
ADC Linker
Type
Peptides
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ala-ala-asn-pab-tfa.html
Purity
90.06
Solubility
10 mM in DMSO
Smiles
OCC1=CC=C(NC([C@H](CC(N)=O)NC([C@H](C)NC([C@@H](N)C)=O)=O)=O)C=C1.O=C(O)C(F)(F)F
Molecular Formula
C19H26F3N5O7
Molecular Weight
493.43
References & Citations
[1]Cheng X, et al. MORAb-202, an Antibody-Drug Conjugate Utilizing Humanized Anti-human FRα Farletuzumab and the Microtubule-targeting Agent Eribulin, has Potent Antitumor Activity. Mol Cancer Ther. 2018 Dec;17 (12) :2665-2675.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Curated Selection
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