Amidepsine D
Amidepsine D is a fungal metabolite isolated from the culture broth of Humicola sp. FO-2942 that inhibits Diacylglycerol acyltransferases (DGAT) activity[1].
Product Specifications
CAS Number
79786-34-8
UNSPSC
12352005
Hazard Statement
H315-H319-H335
Target
Acyltransferase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/amidepsine-d.html
Solubility
10 mM in DMSO
Smiles
O=C(OC1=CC(C)=C(C(O)=O)C(O)=C1)C2=C(C)C=C(OC(C3=C(C)C=C(OC)C=C3OC)=O)C=C2O
Molecular Formula
C26H24O10
Molecular Weight
496.46
Precautions
P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362+P364-P403+P233-P405-P501
References & Citations
[1]Tomoda H, et al. Amidepsines, inhibitors of diacylglycerol acyltransferase produced by Humicola sp. FO-2942. I. Production, isolation and biological properties. J Antibiot (Tokyo) . 1995 Sep;48 (9) :937-41.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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