Amidepsine D

Amidepsine D is a fungal metabolite isolated from the culture broth of Humicola sp. FO-2942 that inhibits Diacylglycerol acyltransferases (DGAT) activity[1].

Product Specifications

CAS Number

[79786-34-8]

UNSPSC

12352005

Hazard Statement

H315-H319-H335

Target

Acyltransferase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/amidepsine-d.html

Solubility

10 mM in DMSO

Smiles

O=C(OC1=CC(C)=C(C(O)=O)C(O)=C1)C2=C(C)C=C(OC(C3=C(C)C=C(OC)C=C3OC)=O)C=C2O

Molecular Formula

C26H24O10

Molecular Weight

496.46

Precautions

P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362+P364-P403+P233-P405-P501

References & Citations

[1]Tomoda H, et al. Amidepsines, inhibitors of diacylglycerol acyltransferase produced by Humicola sp. FO-2942. I. Production, isolation and biological properties. J Antibiot (Tokyo) . 1995 Sep;48 (9) :937-41.