TGFBR1-IN-1
Product Specifications
CAS Number
2170830-26-7
UNSPSC Description
TGFBR1-IN-1 is an ALK5 inhibitor extracted from patent WO2018004290A1, Compound 33, has an IC50 of 10-100 nM[1].
Target Antigen
TGF-β Receptor
Type
Reference compound
Related Pathways
TGF-beta/Smad
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/tgfbr1-in-1.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=NN(C2=NC(C)=CC=C2)C(C3=CC=C4N=CSC4=C3)=C1)NC5=CC=C(O)C=C5
Molecular Weight
427.48
References & Citations
[1]Novel pyrazole derivative as alk5 inhibitor and uses thereof. WO2018004290A1.
Shipping Conditions
Room temperature
Clinical Information
No Development Reported
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