USP7-IN-6
USP7-IN-6 is a potent ubiquitin specific protease 7 (USP7) inhibitor, extracted from patent WO2017212010A1, example 25, has an IC50 of 6.8 nM[1].
Product Specifications
CAS Number
2166586-47-4
UNSPSC
12352005
Target
Deubiquitinase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/usp7-in-6.html
Solubility
10 mM in DMSO
Smiles
O=C1C2=C(N(C3=CC=C(CO)C=C3)C=C2)N=CN1CC4(O)CCN(C([C@H]5[C@H](C6=CC=CC=C6)CN(CC7=CN=C(C8=CC=C(C)N=C8)S7)CC5)=O)CC4
Molecular Formula
C41H43N7O4S
Molecular Weight
729.89
References & Citations
[1]András Kotschy, et al. New (hetero) aryl-substituted-piperidinyl derivatives, a process for their preparation and pharmaceutical compositions containing them. WO2017212010A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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