Delphinidin-3-sambubioside (chloride)

Delphinidin-3-sambubioside (Dp3‐Sam) chloride is an anthocyanin that has orally active anti-inflammatory activity. Delphinidin-3-sambubioside chloride inhibits LPS-induced inflammatory factors release. Delphinidin-3-sambubioside chloride also alleviates hepatic lipid accumulation in HFD rats. Delphinidin-3-sambubioside chloride can be isolated from Hibiscus sabdariffa L.[1][3].

Product Specifications

CAS Number

[53158-73-9]

Product Name Alternative

Dp3‐Sam (chloride)

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Apoptosis

Type

Natural Products

Related Pathways

Apoptosis

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/delphinidin-3-sambubioside-chloride.html

Purity

96.67

Solubility

10 mM in DMSO

Smiles

O[C@@H]1[C@@H](O[C@H]2[C@@H]([C@H]([C@@H](CO2)O)O)O)[C@H](OC3=C(C4=CC(O)=C(O)C(O)=C4)[O+]=C(C=C(O)C=C5O)C5=C3)O[C@H](CO)[C@H]1O.[Cl-]

Molecular Formula

C26H29ClO16

Molecular Weight

632.95

Precautions

H302, H315, H319, H335

References & Citations

[1]Sogo T, et al. Anti-inflammatory activity and molecular mechanism of delphinidin 3-sambubioside, a Hibiscus anthocyanin. Biofactors. 2015 Jan-Feb;41 (1) :58-65. |[2]Hou DX, et al. Delphinidin 3-sambubioside, a Hibiscus anthocyanin, induces apoptosis in human leukemia cells through reactive oxygen species-mediated mitochondrial pathway. Arch Biochem Biophys. 2005 Aug 1;440 (1) :101-9. |[3]Long Q, et al. Delphinidin-3-sambubioside from Hibiscus sabdariffa. L attenuates hyperlipidemia in high fat diet-induced obese rats and oleic acid-induced steatosis in HepG2 cells. Bioengineered. 2021 Dec;12 (1) :3837-3849. https://pubmed.ncbi.nlm.nih.gov/34281481/