A-412997
A-412997 is a selective Dopamine D4 agonist with Ki values of 12 and 7.9 nM for the rat and human receptors. A-412997 improves short term memory and cognitive properties in rodent models[1].
Product Specifications
CAS Number
630116-49-3
UNSPSC
12352005
Target
Dopamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/a-412997.html
Solubility
10 mM in DMSO
Smiles
O=C(NC1=CC=CC(C)=C1)CN2CCC(C3=NC=CC=C3)CC2
Molecular Formula
C19H23N3O
Molecular Weight
309.41
References & Citations
[1]Browman KE, et al. A-412997, a selective dopamine D4 agonist, improves cognitive performance in rats. Pharmacol Biochem Behav. 2005;82 (1) :148-155.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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