MCC-Modified Daunorubicinol
MCC-Modified Daunorubicinol is a drug-Linker conjugates for ADC, which is composed of Modified Daunorubicinol (DNA topoisomerase II inhibitor) and MCC (ADC linker) linked[1].
Product Specifications
CAS Number
[721945-30-8]
UNSPSC
12352203
Target
Drug-Linker Conjugates for ADC
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mc-va-modified-pabc.html
Purity
90.04
Solubility
10 mM in DMSO
Smiles
N[C@H]([C@H](O)[C@H](C)O1)C[C@]1([H])O[C@@H]2C3=C(C[C@](/C(CO)=N/NC(C4CCC(CN5C(C=CC5=O)=O)CC4)=O)(O)C2)C(O)=C6C(C(C7=C(OC)C=CC=C7C6=O)=O)=C3O
Molecular Formula
C39H44N4O13
Molecular Weight
776.79
References & Citations
[1]Samantha Congreve, et al. Antibody drug conjugates (ADC) Current status and mapping of ADC:s in clinical programs.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Daunorubicins/Doxorubicins
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