EC089
EC089 is a cleavable linker used in conjugates of tubulysins and folates, and extracted from patent WO2011069116A1[1].
Product Specifications
CAS Number
[625827-91-0]
UNSPSC
12352203
Hazard Statement
H302-H315-H319-H335
Target
ADC Linker
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ec089.html
Solubility
10 mM in DMSO
Smiles
O=C1C2=NC(CNC3=CC=C(C(N[C@H](C(O)=O)CCC(N[C@@H](CC(O)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(O)=O)C(N[C@@H](CS)C(O)=O)=O)=O)=O)=O)=O)C=C3)=CNC2=NC(N)=N1
Molecular Formula
C36H46N14O14S
Molecular Weight
930.90
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Christopher Paul Leamon, et al. Binding ligand linked drug delivery conjugates of tubulysins. WO2011069116A1.
Shipping Conditions
Room temperature
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Cleavable Linker
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