EC089
Product Specifications
UNSPSC Description
EC089 is a cleavable linker used in conjugates of tubulysins and folates, and extracted from patent WO2011069116A1[1].
Target Antigen
ADC Linker
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ec089.html
Solubility
10 mM in DMSO
Smiles
O=C1C2=NC(CNC3=CC=C(C(N[C@H](C(O)=O)CCC(N[C@@H](CC(O)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(O)=O)C(N[C@@H](CS)C(O)=O)=O)=O)=O)=O)=O)C=C3)=CNC2=NC(N)=N1
Molecular Weight
930.90
References & Citations
[1]Christopher Paul Leamon, et al. Binding ligand linked drug delivery conjugates of tubulysins. WO2011069116A1.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-128940/EC089-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-128940/
Clinical Information
No Development Reported
CAS Number
625827-91-0
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