EC1454
EC1454 is a peptide compound with anticancer activity that targets folate receptor-expressing cancers. EC1454 is a folate-tubulysin conjugate that can be used to prepare drug delivery conjugates for targeted therapy[1].
Product Specifications
CAS Number
1602487-15-9
UNSPSC
12352005
Target
Folate Receptor (FR) ; Liposome
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ec1454.html
Solubility
10 mM in DMSO
Smiles
O=C1C2=NC(CNC3=CC=C(C(N[C@@H](C(O)=O)CCC(N[C@@H](CCC(NC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)=O)C(N[C@H](CCC(O)=O)C(N[C@@H](CCC(NC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)=O)C(N[C@H](CCC(O)=O)C(N[C@@H](CCC(NC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)=O)C(N[C@H](CS)C(O)=O)=O)=O)=O)=O)=O)=O)=O)C=C3)=CNC2=NC(N)=N1
Molecular Formula
C65H98N16O34S
Molecular Weight
1679.63
References & Citations
[1]Christopher Paul LEAMON, et al. Tubulysin Conjugate For Use In Treating Cancer. Patent. US20170348376A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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