NH2-Ph-C4-acid-NH2-Me

NH2-Ph-C4-acid-NH2-Me (PROTAC Linker 31) is an alkyl chain-based PROTAC linker can be used in the synthesis of PROTACs[1].

Product Specifications

CAS Number

[1263819-48-2]

Product Name Alternative

PROTAC Linker 31

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/protac-linker-31.html

Solubility

10 mM in DMSO

Smiles

OC([C@@H](C)C[C@@H](N)CC1=CC=C(N)C=C1)=O

Molecular Formula

C12H18N2O2

Molecular Weight

222.28

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Leverett CA, et al. Design, Synthesis, and Cytotoxic Evaluation of Novel Tubulysin Analogues as ADC Payloads. ACS Med Chem Lett. 2016 Aug 26;7 (11) :999-1004.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Alkyl-Chain Linkers

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