AZD5099
AZD5099, an antibacterial agent, is a potent and selective bacterial topoisomerase II inhibitor. AZD5099 potently inhibits the infections caused by Gram-positive and fastidious Gram-negative bacteria[1].
Product Specifications
CAS Number
907543-25-3
UNSPSC
12352005
Hazard Statement
H302
Target
Bacterial; Topoisomerase
Type
Reference compound
Related Pathways
Anti-infection; Cell Cycle/DNA Damage
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/azd5099.html
Solubility
10 mM in DMSO
Smiles
O=C(C(N=C(N(CC[C@H]1NC(C(NC(C)=C2Cl)=C2Cl)=O)C[C@@H]1OC)S3)=C3C(O)=O)N[C@@H](C)COC
Molecular Formula
C21H27Cl2N5O6S
Molecular Weight
548.44
Precautions
P264-P270-P330-P501
References & Citations
[1]Gregory S Basarab, et al. Optimization of pyrrolamide topoisomerase II inhibitors toward identification of an antibacterial clinical candidate (AZD5099) . J Med Chem. 2014 Jul 24;57 (14) :6060-82.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 1
Isoform
Topo II
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
V9483-100UG 100 µg
Alpha-1-Antichymotrypsin Antibody / AACT / SERPINA3
Sign In for Pricing
View Details 
MBS042559-01 48 Well
Hamster S100 Calcium Binding Protein P ELISA Kit
Sign In for Pricing
View Details MBS042559-02 96 Well
Hamster S100 Calcium Binding Protein P ELISA Kit
Sign In for Pricing
View Details MBS042559-03 5x 96 Well
Hamster S100 Calcium Binding Protein P ELISA Kit
Sign In for Pricing
View Details MBS042559-04 10x 96 Well
Hamster S100 Calcium Binding Protein P ELISA Kit
Sign In for Pricing
View Details