Glucagon receptor antagonist-5
Glucagon receptor antagonist-5 (compound 13K) is a potent and orally bioavailable indazole-based glucagon receptor antagonist (Ki=32 nM) . Glucagon receptor antagonist-5 has potential for the treatment of type 2 diabetes mellitus (T2DM) [1].
Product Specifications
CAS Number
[2200274-63-9]
UNSPSC
12352005
Target
GCGR
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/glucagon-receptor-antagonists-5.html
Solubility
10 mM in DMSO
Smiles
O=C(NCCC(O)=O)C1=CC=C([C@@H](N2N=CC3=C2C=C(C)C(C4=CC=C(C(F)(F)F)C=C4Cl)=C3)CC(C)C)C=C1
Molecular Formula
C30H29ClF3N3O3
Molecular Weight
572.02
References & Citations
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-128781/Glucagon-receptor-antagonists-5-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-128781/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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