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C-Fms-IN-9

C-Fms-IN-9 is a c-FMS inhibitor extracted from patent WO2014145023A1, Compound Example 7. c-Fms-IN-9 inhibits unphosphorylated c-FMS kinase (uFMS) and uKIT with IC50s of [1].

Product Specifications

CAS Number

1628574-50-4

UNSPSC

12352005

Target

C-Fms

Type

Reference compound

Related Pathways

Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/c-fms-in-9.html

Solubility

10 mM in DMSO

Smiles

O=C1N(C2=NC(C)=C(OC3=CC(C4=CN(C)N=C4)=NC=C3)C=C2)NC(C(C)(C)C)=N1

Molecular Formula

C21H23N7O2

Molecular Weight

405.45

References & Citations

[1]Gary E. L. BRANDT, et al. 1,2,4-triazol-5-ones and analogs exhibiting anti-cancer and anti-proliferative activities. WO2014145023A1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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