AM12
AM12 inhibits Lanthanide-evoked TRPC5 activity with an IC50 of 0.28 μM[1].
Product Specifications
CAS Number
[2387510-84-9]
UNSPSC
12352005
Target
TRP Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/am12.html
Solubility
10 mM in DMSO
Smiles
O=C1C(O)=C(C2=CC=CC=C2Br)OC3=C1C(O)=CC(O)=C3
Molecular Formula
C15H9BrO5
Molecular Weight
349.13
References & Citations
[1]Naylor J, et al. Natural and synthetic flavonoid modulation of TRPC5 channels. Br J Pharmacol. 2016 Feb;173 (3) :562-74.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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