AM12
Product Specifications
UNSPSC Description
AM12 inhibits Lanthanide-evoked TRPC5 activity with an IC50 of 0.28 μM[1].
Target Antigen
TRP Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel;Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/am12.html
Solubility
10 mM in DMSO
Smiles
O=C1C(O)=C(C2=CC=CC=C2Br)OC3=C1C(O)=CC(O)=C3
Molecular Weight
349.13
References & Citations
[1]Naylor J, et al. Natural and synthetic flavonoid modulation of TRPC5 channels. Br J Pharmacol. 2016 Feb;173(3):562-74.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-128561/AM12-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-128561/
Clinical Information
No Development Reported
CAS Number
2387510-84-9
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
