JYL-273
JYL-273 is a TRPV1 agonist, with the IC50 of 361 nM in CHO-TRPV1 cell lines[1].
Product Specifications
CAS Number
1391826-17-7
UNSPSC
12352005
Target
TRP Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/jyl-273.html
Solubility
10 mM in DMSO
Smiles
CC(C)(C)C(OCC(CC1=CC=C(C(C)(C)C)C=C1)CC(NCC2=CC=C(O)C(OC)=C2)=S)=O
Molecular Formula
C28H39NO4S
Molecular Weight
485.68
References & Citations
[1]Czikora Á, Lizanecz E, et al. Structure-activity relationships of vanilloid receptor agonists for arteriolar TRPV1. Br J Pharmacol. 2012;165 (6) :1801-1812.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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