AUTEN-67 (inner salt)
Product Specifications
UNSPSC Description
AUTEN-67 (inner salt), the inner salt form of AUTEN-67 (HY-117924), is an orally active autophagy-enhancing agent and MTMR14 inhibitor with potent antiaging and neuroprotective effects. AUTEN-67 (inner salt) hampers the progression of neurodegenerative symptoms in a drosophila model of Huntington's disease[1][2].
Target Antigen
Autophagy
Type
Reference compound
Related Pathways
Autophagy
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/auten-67-inner-salt.html
Solubility
10 mM in DMSO
Smiles
O=C1C([N-]S(=O)(C2=CC=C([N+]([O-])=O)C=C2)=O)=C([N+]3=CNC4=C3C=CC=C4)C(C5=C1C=CC=C5)=O
Molecular Weight
474.45
References & Citations
[1]Diána Papp, et al. AUTEN-67, an autophagy-enhancing drug candidate with potent antiaging and neuroprotective effects. Autophagy. 2016 Feb; 12(2): 273–286.|[2]Viktor Billes, et al. AUTEN-67 (Autophagy Enhancer-67) Hampers the Progression of Neurodegenerative Symptoms in a Drosophila model of Huntington's Disease. J Huntingtons Dis. 2016 May 7;5(2):133-47.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-128477/AUTEN-67-inner-salt-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-128477/
Clinical Information
No Development Reported
CAS Number
301154-74-5
Curated Selection
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