4'-Deoxyphlorizin
4'-Deoxyphlorizin is an inhibitor of the glucose transport system. 4'-Deoxyphlorizi has good phlorizin hydrolase inhibitory activity with the Km value of 0.59 nM and the Ki value of 0.33 nM, respectively[1].
Product Specifications
CAS Number
4319-68-0
UNSPSC
12352005
Target
GLUT
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/4-deoxyphlorizin.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=C(O)C=CC=C1O[C@H]2[C@@H]([C@H]([C@@H]([C@@H](CO)O2)O)O)O)CCC3=CC=C(O)C=C3
Molecular Formula
C21H24O9
Molecular Weight
420.41
References & Citations
[1]J O Evans, et al. The affinity of phlorizin-like compounds for a beta-glucosidase in intestinal brush borders: comparison with the glucose transport system. Arch Biochem Biophys. 1980 Feb;199 (2) :342-8.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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