2,3-Butanediol-d8

2,3-Butanediol-d8 is the deuterium labeled 2,3-Butanediol (HY-128387) [1]. 2,3-Butanediol is microbially derived compound that is a discriminating urinary biomarker of Fmo5-/- mice. 2,3-Butanediol prevents age-related increases in the plasma concentration of cholesterol. 2,3-Butanediol has potential applications in the manufacture of printing inks, perfumes, fumigants, moistening and softening agents, plasticizers, and as a carrier for pharmaceuticals[2][3].

Product Specifications

CAS Number

[347841-77-4]

UNSPSC

12352211

Target

Endogenous Metabolite; Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Metabolic Enzyme/Protease; Others

Applications

COVID-19-immunoregulation

Field of Research

Cardiovascular Disease

Solubility

10 mM in DMSO

Smiles

[2H]C([2H])([2H])C(O)([2H])C(O)([2H])C([2H])([2H])[2H]

Molecular Formula

C4H2D8O2

Molecular Weight

98.17

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Zhang L, et al. Mechanism of 2,3-butanediol stereoisomers formation in a newly isolated Serratia sp. T241. Sci Rep. 2016 Jan 12;6:19257.|[3]Veeravalli S, et al. Treatment of wild-type mice with 2,3-butanediol, a urinary biomarker of Fmo5-/- mice, decreases plasma cholesterol and epididymal fat deposition. Front Physiol. 2022 Aug 8;13:859681.