Waltonitone
Waltonitone is a ursane-type pentacyclic triterpene isolated from Gentian waltonii Burkill. Waltonitone significantly inhibits hepatocellular carcinoma cells growth and induces apoptosis in vitro and in vivo[1].
Product Specifications
CAS Number
[1252676-55-3]
UNSPSC
12352211
Target
Apoptosis
Type
Natural Products
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/waltonitone.html
Solubility
10 mM in DMSO
Smiles
CC1(C)C(CC[C@]2(C)[C@@]3([H])CC=C4[C@]5([H])[C@@H](C)[C@H](C)CC[C@@](CO)5CC[C@](C)4[C@@](C)3CC[C@@]12[H])=O
Molecular Formula
C30H48O2
Molecular Weight
440.70
References & Citations
[1]Zhang Z, et al. Waltonitone induces human hepatocellular carcinoma cells apoptosis in vitro and in vivo.Cancer Lett. 2009 Dec 28;286 (2) :223-31.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
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