CWHM-1552
CWHM-1552 is an orally efficacious inhibitor of P. falciparum with IC50s of 51 nM and 53 nM for 3D7 and Dd2 strain, respectively[1].
Product Specifications
CAS Number
[2368253-58-9]
UNSPSC
12352005
Target
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/cwhm-1552.html
Solubility
10 mM in DMSO
Smiles
CN(C)C1=CC=C(CC(N[C@@H]2CNC[C@H]2C3=CC=C(C(F)(C)F)C=C3)=O)C=C1
Molecular Formula
C22H27F2N3O
Molecular Weight
387.47
References & Citations
[1]Meyers MJ, et al. 4-Aryl Pyrrolidines as Novel Orally Efficacious Antimalarial Agents. Part 2: 2-Aryl-N- (4-arylpyrrolidin-3-yl) acetamides. ACS Med Chem Lett. 2019 May, 10 (6) :966-971.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Plasmodium
Curated Selection
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