FIPI (hydrochloride)
FIPI hydrochloride is a phospholipase D (PLD) inhibitor with an IC50 for PLD1 and PLD2 of about 25 nM. FIPI hydrochloride regulates cytoskeletal recombination, cell diffusion and chemotaxis. FIPI hydrochloride can be used in cancer research. In addition, FIPI hydrochloride can enhance the secretion and aggregation of platelet dense particles, inhibit thrombosis, reduce ischemic stroke infarct volume and improve nerve function[1][2][3].
Product Specifications
CAS Number
1781834-93-2
Product Name Alternative
5-Fluoro-2-indolyl deschlorohalopemide (hydrochloride)
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Phospholipase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology; Neurological Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/fipi-hydrochloride.html
Solubility
10 mM in DMSO
Smiles
O=C(NCCN1CCC(CC1)N2C3=CC=CC=C3NC2=O)C4=CC5=C(C=CC(F)=C5)N4.[H]Cl
Molecular Formula
C23H25ClFN5O2
Molecular Weight
457.93
Precautions
P261-P280-P302+P352
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PLD
Frequently Asked Questions
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