Cycloguanil
Product Specifications
UNSPSC Description
Cycloguanil, the active metabolite of Proguanil, acts on malaria schizonts in erythrocytes and hepatocytes[1].
Target Antigen
Drug Metabolite; Parasite
Type
Reference compound
Related Pathways
Anti-infection;Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/cycloguanil.html
Solubility
10 mM in DMSO
Smiles
NC1=NC(N)=NC(C)(C)N1C2=CC=C(Cl)C=C2
Molecular Weight
251.72
References & Citations
[1]Matthaei J, et al. OCT1 Deficiency Affects Hepatocellular Concentrations and Pharmacokinetics of Cycloguanil, the Active Metabolite of the Antimalarial Drug Proguanil. Clin Pharmacol Ther. 2019 Jan;105(1):190-200.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-12784/Cycloguanil-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-12784/
Clinical Information
No Development Reported
CAS Number
516-21-2
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