SCH 50911 (hydrochloride)
SCH 50911 hydrochloride, (+) - (S) -5,5-dimethylmorpholinyl-2-acetic acid, a selective, orally-active and competitive γ-Aminobutyric acid B GABA (B) receptor antagonist, binds to GABA (B) receptor with IC50 of 1.1 μM. SCH 50911 hydrochloride antagonizes GABA (B) autoreceptors, increasing the electrically-stimulated 3H overflow with an IC50 of 3 μM.
Product Specifications
CAS Number
160415-07-6
UNSPSC
12352005
Hazard Statement
H317
Target
GABA Receptor
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/sch-50911-hydrochloride.html
Solubility
10 mM in DMSO
Smiles
O=C(O)C[C@H]1CNC(C)(C)CO1.[H]Cl
Molecular Formula
C8H16ClNO3
Molecular Weight
209.67
Precautions
P261-P272-P280-P302+P352-P362+P364-P501
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
