Clofezone
Clofezone (Perclusone) is an antirheumatic agent that inhibits collagen formation in rat Chondrus granulomas. Clofezone can be used in the study of various rheumatic diseases, especially arthritis (RA) and ankylosing spondylitis (AS) [1][2].
Product Specifications
CAS Number
17449-96-6
Product Name Alternative
Perclusone
UNSPSC
12352005
Target
Collagen
Type
Reference compound
Related Pathways
Cytoskeleton
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/clofezone.html
Solubility
10 mM in DMSO
Smiles
O=C(COC1=CC=C(C=C1)Cl)NCCN(CC)CC.O=C(N(N(C2=O)C3=CC=CC=C3)C4=CC=CC=C4)C2CCCC
Molecular Formula
C33H41ClN4O4
Molecular Weight
593.16
References & Citations
[1]Celik CM. Erfahrungen in der Behandlung rheumatoider Erkrankungen mit unterschiedlichen Clofezon-Dosen [Experiences in the management of rheumatoid diseases using different clofezone doses]. Z Rheumatol. 1976 May-Jun;35 (5-6) :240-7. |[2]Brettschneider I, et al. Effect of some antirheumatics on connective tissue components. Arzneimittelforschung. 1976;26 (5) :846-8.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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