Pteropterin

Pteropterin (Pteroyltriglutamic) is an active form of folate. Pteropterin shows inhibiting effect on tumor growth and has broad anticancer activity[1][2].

Product Specifications

CAS Number

[89-38-3]

Product Name Alternative

Pteroyltriglutamic

UNSPSC

12352005

Target

Drug Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/pteropterin.html

Purity

99.31

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(CC[C@H](NC(CC[C@H](NC(CC[C@H](NC(C1=CC=C(C=C1)NCC2=CN=C3NC(N)=NC(C3=N2)=O)=O)C(O)=O)=O)C(O)=O)=O)C(O)=O)O

Molecular Formula

C29H33N9O12

Molecular Weight

699.63

References & Citations

[1]Stine ZE, et al. Targeting cancer metabolism in the era of precision oncology. Nat Rev Drug Discov. 2022 Feb;21 (2) :141-162. |[2]Muthu M, et al. Current Status and Future Prospects of Clinically Exploiting Cancer-specific Metabolism-Why Is Tumor Metabolism Not More Extensively Translated into Clinical Targets and Biomarkers? Int J Mol Sci. 2019 Mar 19;20 (6) :1385.