Piribedil (hydrochloride)
Piribedil hydrochloride is a potent and orally active dopamine D2 and dopamine D3 agonist. Piribedil hydrochloride is also a α2-adrenoceptors antagonist. Piribedil hydrochloride can inhibit MLL1 methyltransferase activity (EC50: 0.18 μM) . Piribedil hydrochloride has the potential for the research of parkinson's disease, circulatory disorders, cancers[1][2][3][4].
Product Specifications
CAS Number
78213-63-5
UNSPSC
12352005
Target
Adrenergic Receptor; Dopamine Receptor; Histone Methyltransferase
Type
Reference compound
Related Pathways
Epigenetics; GPCR/G Protein; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Cancer; Endocrinology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/piribedil-hydrochloride.html
Solubility
10 mM in DMSO
Smiles
[H]Cl.C1(N2CCN(CC3=CC=C(OCO4)C4=C3)CC2)=NC=CC=N1
Molecular Formula
C16H19ClN4O2
Molecular Weight
334.80
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
D2 Receptor; D3 Receptor; α adrenergic receptor
Frequently Asked Questions
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