Yuanhuadin

Yuanhuadin, extracted from Genkwa Flos Daphne genkwa, has antitumor activity through inhibiting Akt/mTOR and EGFR pathways, induce cell-cycle arrest and abortion[1].

Product Specifications

CAS Number

[76402-66-9]

UNSPSC

12352005

Target

Akt; EGFR; mTOR

Type

Natural Products

Related Pathways

JAK/STAT Signaling; PI3K/Akt/mTOR; Protein Tyrosine Kinase/RTK

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/yuanhuadin.html

Solubility

10 mM in DMSO

Smiles

O=C1C(C)=C[C@@H]2[C@]3([C@H]4[C@H]5O[C@@]5([C@H]([C@@]12O)O)CO)O[C@]6(O[C@@]([C@@H](OC(C)=O)[C@H]3C)([C@H]4O6)C(C)=C)/C=C/C=C/CCCCC

Molecular Formula

C32H42O10

Molecular Weight

586.67

References & Citations

[1]Christian Bailly, et al. Yuanhuacin and Related Anti-Inflammatory and Anticancer Daphnane Diterpenes from Genkwa Flos—An Overview. Biomolecules. 2022 Feb; 12 (2) : 192.