Sulfo DBCO-amine
Sulfo DBCO-amine is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Sulfo DBCO-amine is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
Product Specifications
CAS Number
[2028284-70-8]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/sulfo-dbco-amine.html
Purity
99.00
Solubility
10 mM in DMSO
Smiles
O=C(N1CC2=C(C#CC3=C1C=CC=C3)C=CC=C2)CCNC(C(S(=O)(O)=O)CN)=O
Molecular Formula
C21H21N3O5S
Molecular Weight
427.47
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Alkyl-Chain Linkers
Available Sizes
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