SP-Chymostatin B

SP-Chymostatin B (α-MAPI) is a strong inhibitor of many proteases, including chymotrypsin, papain, chymotrypsin-like serine proteinases, chymases, and lysosomal cysteine proteinases such as cathepsins A, B, C, H, and L. SP-Chymostatin B weakly inhibits human leucocyte elastase[1].

Product Specifications

CAS Number

[70857-49-7]

Product Name Alternative

α-MAPI

UNSPSC

12352005

Target

Elastase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/sp-chymostatin-b.html

Solubility

10 mM in DMSO

Smiles

O=C(O)[C@H](CC1=CC=CC=C1)NC(N[C@@H](CCCNC(N)=N)C(N[C@@H](C(C)C)C(N[C@H](C=O)CC2=CC=CC=C2)=O)=O)=O

Molecular Formula

C30H41N7O6

Molecular Weight

595.69

References & Citations

[1]Syuichi Oka, et al. Protease Inhibitors Produced by Streptomyces libani. Agricultural and Biological Chemistry, Volume 43, Issue 4, 1 April 1979, Pages 691–696