Mycro2

Mycro2 is an inhibitor of c-Myc/Max dimer and DNA binding, with an IC50 value of 23 μM for the inhibition of Myc/Max DNA binding activity. Mycro2 can inhibit c-myc-dependent cell proliferation, gene transcription and oncogenic transformation[1].

Product Specifications

CAS Number

314049-21-3

UNSPSC

12352005

Target

C-Myc

Type

Reference compound

Related Pathways

Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/mycro2.html

Purity

99.81

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

O=C(C1=NN2C(C(F)(F)F)=CC(C3=CC=CS3)=NC2=C1)NCC4=CC=CS4

Molecular Formula

C17H11F3N4OS2

Molecular Weight

408.42

References & Citations

[1]Anke Kiessling, et al. Selective inhibition of c-Myc/Max dimerization and DNA binding by small molecules. Chem Biol. 2006 Jul;13 (7) :745-51.|[2]Kiessling A, et al. Selective inhibition of c-Myc/Max dimerization and DNA binding by small molecules. Chem Biol. 2006 Jul;13 (7) :745-51.