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BI-1230

BI-1230, a chemical probe, is potent and digit nanomolar inhibitor of HCV NS3 protease and of viral replication. BI-1230 is also highly selective against other serine/cysteine proteases. BI-1230 shows good Pharmacokinetic (PK) activity[1].

Product Specifications

CAS Number

[849022-32-8]

UNSPSC

12352005

Target

HCV Protease

Type

Reference compound

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/bi-1230.html

Solubility

10 mM in DMSO

Smiles

O=C([C@]([C@]1([H])/C=C\CCCCC[C@@H]2NC(OC3CCCC3)=O)(C1)NC([C@@](C[C@@H](OC4=CC(C5=CSC(NC(C(C)C)=O)=N5)=NC6=C(C)C(OC)=CC=C46)C7)([H])N7C2=O)=O)O

Molecular Formula

C42H52N6O9S

Molecular Weight

816.96

References & Citations

[1]Overview for BI-1230 an inhibitor of HCV NS3

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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